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Knockout ALD
Knockout ALD is a non-profit dedicated to raising awareness of and funds for adrenoleukodystrophy research.
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Knockout ALD is a non-profit dedicated to raising awareness of and funds for adrenoleukodystrophy research.
Knockout ALD is a tax-exempt 501(c)(3) nonprofit organization. Your generous gift is tax-deductible and will help us fund research projects at the University of Minnesota (a world leader in ALD treatment and research) that are working to improve treatments options that lead to better outcomes for ALD boys.
Adrenoleukodystrophy (ALD) is a rare, genetic disease that progressively damages the adrenal glands, spinal cord, and myelin of the nervous system. It most severely affects boys, but can cause a range of neurological and physical symptoms in men and women. Early diagnosis and treatment is key, especially with cerebral ALD which can be fatal if not treated early.
Please click the "About Us" tab above to learn about our cause, our Run for ALD, our partners, and other ways to help.
You can make a donation through the PayPal button (fees are taken out from your donation), or mail a check directly to Knockout ALD, 1551 Timberlake Manor Parkway, Chesterfield, MO 63017.
**Donations also can be made on Venmo @KnockoutALD.
Together, we can make a difference and help Cure the Boys!

Knockout ALD is thrilled and thankful with the success of our 9th Annual Run for ALD which was our biggest event yet! THANK YOU to our sponsors and the over 700 participants near and far who helped raise awareness of ALD and
over $45,000 for ALD research at the University of Minnesota.
Our total lifetime funds raised for ALD research at the University of Minnesota now exceeds $350,000! These funds help to push forward research that is working towards better treatments and better outcomes for ALD boys. THANK YOU!
Donations can be made anytime throughout the year through our Paypal link above or by Venmo @KnockoutALD.
We wish you many blessings in the new year and look forward to our 10th Annual Run for ALD in 2026!



















Knockout ALD in the NEWS!
Check out our interview on KMOV St. Louis for Rare Disease Day!
https://www.kmov.com/video/2023/02/27/rare-neurological-disorder-added-missouri-newborn-screening/
We can't wait to see you for our next Run for ALD on Nov. 22nd in Creve Coeur, MO!
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It was an amazing day in honor and memory of our ALD warriors, and we are so grateful for your support and participation in helping us Knockout ALD!
Sign up to learn more about our cause and our next Run for ALD event!
Check out this great video of so many reasons why we are devoted to this cause dear to our hearts. Thanks to our friends in Minnesota and their nonprofit X out ALD, whom we partner with to raise funds for University of Minnesota ALD Research.
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THANK YOU for helping us make our 9th Annual Run for ALD our largest event ever! Over 700 participants near and far helped raise awareness and over $45,000 for ALD research!